Human chorionic gonadotropin (hCG) and prevention of breast cancer
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چکیده
منابع مشابه
Human chorionic gonadotropin (hCG) and prevention of breast cancer.
Animal and 'in vitro' experiences learned that human chorionic gonadotropin (hCG) is capable to protect from breast cancer. Receptors for hCG/luteinizing hormone (LH) are present on human female and male breast cancer cells. hCG decreases proliferation and invasion of breast cancer MCF-7 cells by inhibiting NF-kappa B, AP-1 activation and other genes. Doxorubicin toxicity is enhanced by conjuga...
متن کاملHuman chorionic gonadotropin (HCG) induction of apoptosis in breast cancer.
10658 Background: Apoptotic induction in cancer cells may improve the efficacy of local or systemic therapy. Human Chorionic Gonadotropin (HCG) injection directly into Kaposi's sarcoma or melanoma has been shown to increase the apoptotic index in these tumor types. The rapid induction of apoptosis in breast cancer immediately preceding local or systemic therapy may improve the response to thera...
متن کاملHuman Chorionic Gonadotropin and Breast Cancer
Breast cancer is well known as a malignancy being strongly influenced by female steroids. Pregnancy is a protective factor against breast cancer. Human chorionic gonadotropin (HCG) is a candidate hormone which could mediate this antitumoral effect of pregnancy. For this review article, all original research articles on the role of HCG in breast cancer were considered, which are listed in PubMed...
متن کاملHuman chorionic gonadotropin (hCG) versus magnesium sulfate to arrest preterm
Introduction: Considering the high incidence of preterm labor and its known complications, and that human myometrium contains receptors for human chronic gonadotropin (hCG) and that hCG can inhibit myometrial contractions on vitro, made me study treating effects of hCG on preterm labor. This clinical trial study was carried out to compare the effect of hCG, and magnesium sulfate (mgso4) on pre...
متن کاملTreatment with human chorionic gonadotropin and risk of breast cancer.
Studies of the induction of mammary tumors by 7,12-dimethylbenz(a)anthracene in a rat model show that human chorionic gonadotropin (hCG) administration reduces tumor incidence in a manner comparable to that of a completed pregnancy. On the basis of their studies, Russo and Russo (Cancer Epidemiol., Biomarkers & Prev., 3: 353-364, 1994) have proposed that hCG treatment of young nulliparous women...
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ژورنال
عنوان ژورنال: Molecular and Cellular Endocrinology
سال: 2007
ISSN: 0303-7207
DOI: 10.1016/j.mce.2006.06.015